Data on Prostate Cancer in Ghana

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Klufio conducted a retrospective analysis of the frequency and pattern of genitourinary (GU) cancers seen at the Korle-Bu Teaching Hospital, in Accra, between 1980 and 1990. According to this study, prostate cancer accounted for 349/479 GU cancers in males (81.4 percent). Wiredu and Armah conducted a similar analysis for all cancers at the same institution between 1991 and 2000. In this study, prostate cancer accounted for 17.35 percent of all cancers identified (635/3,659) in males and females and about 31.8 percent of all cancers in males.

The GLOBOCAN 2002 database (compiled by Ferlay et al. for the International Agency for Research on Cancer) provides the following data for prostate cancer in Ghana:

  • Estimated number of new cases per year: 921
  • Estimated age-standardized rate of new cases per year: 19.3/100,000
  • Estimated number of deaths per year: 758
  • Estimated age-standardized number of deaths per year: 16.0/100,000
  • Estimated 1-year prevalence: 734
  • Estimated 5-year prevalence: 2,451

The WHO Impact of Cancer in Your Country data tables provide the following data for prostate cancer in Ghana:

  • Estimated age-standardized incidence (in 2002): 71/100,000
  • Estimated age-standardized death rate (in 2005): 55/100,000

Zeigler-Johnson et al. have demonstrated clear ethic differences in genotypes for genes associated with androgen metabolism, including the SRD5A2 and CYP3A4 alleles. They showed that Ghanaian, Senegalese, and African-American males have the highest frequency of alleles previously associated with increased prostate cancer risk.

If you know of additional sources of specific or current information about the incidence, prevalence and mortality of prostate cancer in Ghana, we would be interested in learning about them. Please post such information in the comment box below.

Content on this page last reviewed and updated October 26, 2008

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